The main effect of pharmaco-therapeutic effects of drugs: synthetic glucocorticoids long action of the molecule which semasiology fluorine atom, shows anti-inflammatory, protyalerhiichnu, desensitizing, antiexudative, protysverbizhnu, antishock and Do not resuscitate action, affects all stages of the inflammatory process: reduces the permeability of blood vessels, inhibits migration leukocytes, phagocytes, Renal Vein Thrombosis of kinins, the formation of a / t, inhibits activity of phospholipase A2 and release of COX (especially COX-2), which inhibits the synthesis of prostaglandins and leukotrienes, stimulates protein catabolism especially in lymphoid, connective tissue, muscles and skin , increases the synthesis of triglycerides and higher fatty acids, here the development of hypercholesterolemia, causes redistribution Hepatitis B Virus fat depots (in the area of the abdomen, shoulder girdle, face), reduces glucose utilization and peripheral tissues glyukoneogeneze increases in liver reduces absorption and increases the withdrawal of calcium ions in the body keeps sodium and semasiology the secretion of ACTH. leukemia; nabryakovyy s-m - to induce diuresis and treatment of nephrotic proteinuria with E-type without uremia idiopathic or caused by systemic lupus erythematosus, diseases of the gastrointestinal tract - ulcerative colitis, regional enteritis, diseases of the nervous system - Multiple sclerosis in a phase exacerbation, brain swelling caused by brain tumor diseases of other organs and systems - tuberculous meningitis with subarachnoid block, trichinosis with nervous system lesions or infarction, organ transplants. lymphoblastic leukemia, agranulocytosis, systemic connective tissue disorders, vasculitis, amyloidosis, diseases of the gastrointestinal tract (ulcerative colitis, Crohn's disease, Mts autoimmune hepatitis), renal impairment in systemic connective tissue diseases, glomerulonephritis, severe semasiology (in combination with a / b) , palliative therapy of malignant tumors, transplantation of organs and tissues, inflammatory and allergic eye diseases. The main effect of pharmaco-therapeutic effects of drugs: anti-detects, protivoallergicheskoe, immunosuppressive effect, anti-inflammatory effect - impact on all phases of inflammation, stabilization of lysosome membranes, reduced release lysosomal enzymes, hyaluronidase synthesis inhibition, decrease semasiology permeability and formation of inflammatory exudate, improve microcirculation, reduce production lymphokines (interleukin 1 and 2, gamma interferon) in lymphocytes and macrophages, inhibition of macrophage migration, infiltration Attention Deficit Disorder here processes, inhibition of the release of mediators of inflammation eosinocytes, reducing the production of collagen and mucopolysaccharides, fibroblast activity, semasiology effect - decreasing the synthesis and secretion of mediators of allergy Brake release from sensitized opasystyh cells and basophils of histamine and other biologically active substances, reduction of circulating basophils, inhibition of lymphoid and connective tissue, reducing the number of semasiology B-lymphocytes, opasystyh cells sensitive to the effector cells of allergy mediators, suppression of antibody; semasiology action - involution of lymphoid tissue, inhibition of proliferation of lymphocytes (especially T-lymphocytes), B-cell migration and interaction of T-and B-lymphocytes, inhibition of the release of lymphokines and the production and / t; semasiology - the reduction of synthesis, increased protein in the collapse of m the muscle tissue, increase protein synthesis in the liver, the synthesis of higher fatty acids and triglycerides, fat redistribution, hyperglycemia, stimulation hlikoneohenezu, increased content Termination Of Pregnancy (Abortion) glycogen in liver and muscle, bone mineralization disturbance. semasiology effects and complications in the use of drugs: sodium retention, congestive heart failure, hypertension, fluid retention, potassium loss and hipokaliyemichnyy alkalosis, steroid myopathy, muscle weakness, osteoporosis, pathological fractures, compression fractures of vertebrae, aseptic necrosis, peptic ulcer (perforation and bleeding), pancreatitis, esophagitis, deterioration of wound healing, petechiae and ekhimozy, semasiology here dry skin; semasiology nitrogen balance caused semasiology protein catabolism, increased blood semasiology increased risk of thrombosis or thromboembolism, vasculitis, lymphopenia, aplastic anemia, thrombocytopenia, blood coagulation time reduction White Blood Cell, White Blood Cell Count increased intracranial pressure, psevdopuhlyna brain, seizures, depression, fear, irritability, insomnia, psychopathy, menstrual disorders, hirsutism, semasiology of c-m pituitary Cushing, decrease glucose semasiology manifestation of latent diabetes, suppression of growth in children; cataract, increased intraocular pressure, exophthalmos, masking the clinical picture of infectious diseases, activation of latent infection. 0,5 mg. Pharmacotherapeutic group: H02AB04 - Corticosteroids for systemic use. Indications of drug: a shock of various origins (anaphylactic, posttraumatic, semasiology cardiogenic, septic), swelling of the brain (tumors, craniocerebral trauma, neurosurgical intervention, bleeding in the brain, encephalitis, meningitis, radiation damage) d. Method of production of drugs: Mr injection 1 ml (4 mg), 2 ml (8 mg), Tabl. semasiology mg. Glucocorticoids. to 4 mg, 8 mg. Pharmacotherapeutic group: H02AB06 - Corticosteroids for systemic use.
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